This review article by Sarah Boyle is part of a collection of articles highlighting the breadth and depth of research being undertaken in basic endocrinology by early- and mid-career researchers.

It nicely gathers current knowledge regarding the association of hormone receptor profiles with composition of the microenvironment; how hormones directly influence stromal cells, immune cells and cells associated with the vasculature; and the paracrine mechanisms that lead to the formation of a tumour-promoting extracellular matrix.

The article provides a valuable and timely review, which shows the increasing importance of hormone receptors in cancer cell proliferation and malignant properties of cancers.

Read the full article in Journal of Molecular Endocrinology 70 e220174