The end of 2022 brought with it a very timely review article from Juhlin et al. in the area of thyroid tumours. The authors cover the fifth edition of the World Health Organization (WHO) Classification of Endocrine and Neuroendocrine Tumors. This new edition brings in the latest molecular findings in thyroid pathology, to give a new focus on diagnostics and treatments.

With this fifth edition, we see appropriate changes to nomenclature, grading and prognostication of thyroid proliferations, based on pathologic features and molecular profile. It is crucial that endocrinologists and practising physicians who manage thyroid nodules acquaint themselves with this new classification scheme, as tumour entities have been renamed to take into account underlying tumour biology and/or histogenesis, as well as molecular profiles.

Read the full article in Endocrine-Related Cancer doi:10.1530/ERC-22-0293